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2017
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  Journal of Medicine, Radiology, Pathology & Surgery (2017), No.5, Vol 4, September-October Issue  
 
 
 
1 . ORIGINAL ARTICLE
Extracellular matrix changes in oral squamous cell carcinoma using special stains
Pratijya Raj, Veda Hegde, Wasim Raja Mumtaz
Full Text PDF |   Abstract



ABSTRACT

Background: Squamous cell carcinoma (SCC) is the most frequent malignancy of the oral cavity which is known to have a high mortality rate. During the invasion, tumor cells break through the basement membrane, penetrate the connective tissue, are embedded in or surrounded by the extracellular matrix (ECM), producing reactive changes in stroma. It is an established fact that tumor stroma plays a vital role in tumor progression. The ECM has an important role in tissue organization and function.

Aims: The aim of the study is to assess whether special stains are useful in detecting ECM changes early invasive and well-established oral SCC (OSCC) using special stains.

Materials and Methods: This retrospective study constitutes a total of 30 cases examined to study changes in ECM at early invasive and well-established OSCC cases. Two sections each was obtained from above study groups and were subjected to Van Gieson and Periodic Acid Schiff’s (PAS) stains respectively, and were compared with routine hematoxylin and eosin stain. Interpretation of staining intensity was carried out and statistically analyzed.

Results: Matrix changes were noted using special stains in both early invasive and well-established OSCC as seen in their staining characteristics.

Conclusion: PAS and Van Gieson are indeed useful in detecting changes in glycoprotein and collagen in well-established OSCC and early invasive OSCC.

Keywords: Early invasion, extracellular matrix, oral squamous cell carcinoma, periodic acid Schiff’s, Van Gieson

How to cite this article: Raj P, Hegde V, Mumtaz WR. Extracellular matrix changes in oral squamous cell carcinoma using special stains. J Med Radiol Pathol Surg 2017;4:1-4

Received: 08 July 2017;

Accepted: 29 August 2017

 
2 . ORIGINAL ARTICLE
Personal identification using frontal sinus and nasal septum patterns in forensic medicine: A retrospective digital radiographic study
Tejavathi Nagaraj, Haritma Nigam, H. N. Santosh, C. K. Sumana, Sita Gogula, Poonam Sahu
Full Text PDF |   Abstract



ABSTRACT

Background: Deviation in patterns of frontal sinus (FS) and nasal septum (NS) help in identifying the deceased or alive in forensic medicine.

Aim: The present study was performed for gender determination and personal identification by observing the various patterns of FS and NS in posteroanterior (PA) cephalogram.

Materials and Methods: A total of 280 individuals between the age interval of 20 and 50 years were selected. PA cephalogram of the selected individuals was taken on ortho pantomo graph machine with cephalography attachment and Orthophos DS; Sidexis XG digital radiography system.

Results: In FS, symmetrical pattern 219 (78%), and in NS, straight 92 (33%) and sigmoid 91 individuals (33%) were found to be dominant. Both FS and NS patterns were also assessed together for each individual. Pearson’s correlation coefficient was done, and r value was 0.994 with P < 0.00001 (P < 0.05) showing it as highly significant.

Conclusion: Usage of FS and NS patterns acts as an indicator for personal identification in forensic medicine.

Keywords: Forensic, frontal sinus, nasal septum

How to cite this article: Nagaraj T, Nigam H, Santosh HN, Sumana CK, Gogula S, Sahu P. Personal identification using frontal sinus and nasal septum patterns in forensic medicine: A retrospective digital radiographic study. J Med Radiol Pathol Surg 2017;4:5-8.

Received: 18 July 2017

Accepted: 20 August 2017

 
3 . ORIGINAL ARTICLE
Diagnostic accuracy of cone beam computed tomography with and without metal artifact reduction algorithm in detection of vertical root fractures of teeth with metallic posts
Islam S. Shaker, Nashwa S. Mohamed, Ahmed M. Abdelsamad
Full Text PDF |   Abstract



ABSTRACT

Background: In cone beam computed tomography (CBCT), metallic structures can cause artifacts in the images, since most teeth suspected to have vertical root fractures (VRF) are endodontically treated and have a metallic post in the root canal, fracture detection may pose a challenge.

Aim: This study aimed to determine the diagnostic accuracy of CBCT using metal artifact reduction (MAR) algorithm in detection of VRF of teeth with metallic posts.

Materials and Methods: A total of 120 single-rooted extracted human teeth were obtained and endodontically treated then placed in an acrylic block, and metallic posts were inserted. After post insertion, the teeth roots were divided into two groups one with induced VRF and the other having intact roots with the posts inserted. Then, each tooth was coded and imaged by CBCT with and without using MAR algorithm.

Results: Using the MAR algorithm improved the diagnostic accuracy but with no statistically significant difference.

Conclusion: In case of presence of metallic posts, CBCT with MAR algorithm can be used to detect VRF.

Keywords: Cone beam computed tomography metal artifact, vertical root fractures, vertical root fractures cone beam computed tomography

How to cite this article: Shaker IS, Mohamed NS, Abdelsamad AM. Diagnostic accuracy of cone beam computed tomography with and without metal artifact reduction algorithm in detection of vertical root fractures of teeth with metallic posts. J Med Radiol Pathol Surg 2017;4:9-12.

Received: 20 July 2017;

Accepted: 29 September 2017

 
4 . ORIGINAL ARTICLE
Attitude toward tobacco and alcohol practices among dental undergraduate students: A questionnaire survey
Manav Chaturvedi, S. V. Sreelatha
Full Text PDF |   Abstract



ABSTRACT

Background: Just like other adults, dental graduates to have inclination toward habits such as consumption of tobacco and alcohol. Our study aimed to find the number of dental graduates indulged in this bad habit. This is an important study as it assesses the true awareness among dental graduates who being medical professionals are an active part of health promotion and prevention campaigns.

Materials and Methods: A questionnaire-based survey was conducted for all the 4-years volunteer dental graduates.

Results: Consumption of both tobacco and alcohol was increased over the subsequent years. Based on gender, females were less likely indulged in these habits. Majority consumed cigarette smoking form of tobacco and beer was the most used alcoholic beverage.

Conclusion: A very small percentage of students showed excessive tobacco and alcohol use, and it is for this group that education on the consequences of tobacco and alcohol abuse would be most relevant. There should be a role for higher education, community, and professional bodies to participate actively in the prevention of tobacco and alcohol abuse among undergraduates.

Keywords: Dental, smoking, students, tobacco

How to cite this article: Chaturvedi M, Sreelatha SV. Attitude toward tobacco and alcohol practices among dental undergraduate students: A questionnaire survey. J Med Radiol Pathol Surg 2017;4:13-16.

Received: 11 July 2017;

Accepted: 20 September 2017

 
5 . ORIGINAL ARTICLE
To study the role of various magnetic resonance imaging sequences in assessment of vertebral marrow changes in postmenopausal Indian female population
Shagufta Wahab, Ibne Ahmad
Full Text PDF |   Abstract



ABSTRACT

Background: Magnetic resonance imaging (MRI) appearance of vertebral bone marrow is highly variable varying with age and menopause in females. The differential appearance of marrow on various sequences can be used for assessing the marrow and studying the changes which are physiological with age and the changes which represent pathology.

Objective: The aim and purpose of this study is to evaluate the patterns of changes in the appearance of vertebral bone marrow occurring with age and menopause in Indian females on MRI.

Materials and Methods: MRI images of 60 female subjects -0.30 pre-menopausal females more than 25 years (25-35 and 35-45 years age group) and 30 post-menopausal females (45-55, 55-65, and more than 65 years age group) were evaluated. MRI was performed on 1.5 Tesla MRI Machine (Siemens Magnetom Avanto) and T1, T2 weighted and STIR images obtained in sagittal, axial, and coronal planes from D8 to L4 levels.

Results: There was variation in the appearance of bone marrow among individuals with increasing fat content with age and menopause. It usually followed large globular fat deposition pattern (Pattern 4 described by Ricci et al.) in 60% of post-menopausal group and all cases more than 65 years of age had almost homogenously increased signal intensity of vertebrae probably due to prevalent osteoporosis in post-menopausal Indian females. None of the cases in post-menopausal group had fine punctuated fatty replacement of bone marrow (Pattern 3 described by Ricci et al.).

Conclusions: MRI is a very helpful imaging modality in the evaluation of vertebral marrow changes with age and menopause but as the marrow is a tissue undergoing constant change its appearance on MRI is highly variable, and its accurate analysis requires radiological, acumen, expertise and a correct combination of various MRI pulse sequences.

Keywords: Fatty replacement, magnetic resonance imaging sequences, vertebral marrow

How to cite this article: Wahab S, Ahmad I. To study the role of various magnetic resonance imaging sequences in assessment of vertebral marrow changes in postmenopausal Indian female population. J Med Radiol Pathol Surg 2017;4:17-20.

Received: 21 July 2017;

Accepted: 29 September 2071

 
6 . CASE REPORT
Oral lichen planus bullous variety: A case report
T. Dhanraj, Swetha Paulose, L. Kavya, Yoga Sivakumar
Full Text PDF |   Abstract



ABSTRACT

Lichen planus (LP)is a common immune-mediated chronic mucocutaneous disorder with a worldwide distribution. It mainly affects the skin, nails, hair, and the genital area. Initial presentation of these lesions may occur in the oral mucosa without any other cutaneous manifestations. Hence, it is necessary for the dental professionals to be both familiar with its varied clinical presentations, course of this condition, and their management. Here, we report a case of bullous LP in a 23-year-old male patient, discussing clinical features, etiopathogenesis, and management.

Keywords: Bullous lichen planus, direct immunofluorescence, oral lichen planus

How to cite this article: Dhanraj T, Paulose S, Kavya, Sivakumar Y. Oral lichen planus bullous variety A case report. J Med Radiol Pathol Surg 2017;4:21-23.

Received: 07 June 17;

Accepted: 15 July 17

 
 
     
 
   
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